If by "clip" you mean magazine, the answer is yes, a Ruger .22 rifle can be fired without a magazine. It is a pain in the butt for most rifles though. I'm guessing you are talking about a 10/22 semiauto and it is definately awkward to load one round at a time.
I assume you know very little about firearms and are going to be doing some sort of report or story involving this scenario, so let me help you out by informing you that an ammunition feeding device which completely encloses the rounds is a magazine, not a clip. A clip is something different that is usually used to load a magazine and holds ammo without enclosing it.
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