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I wouldn't shoot them in an alloy framed .38 Special (I know I'm the one who posted that data, but that was 2 1/2 years ago based just on a Quickload calculation) but I might load it in .38 Special brass and shoot it in an alloy .357 Magnum. It would probably be great loaded in .357 brass (maybe even upped just a little) for a reduced-power Magnum load.
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So what's the rule going beyond published data, do you just slowly work up till you see messed up primers or sticky cases?