@ moloch
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Shoot the throat! If you hit the throat veins he will be dead in seconds.
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I'm afraid that's not true. Firstly the venous return is not as critical as the arterial supply. Secondly the arterial supply is duplicated on the left and right side of the neck (the carotid and vertebral arteries are in pairs and there is intracerebral crossover). Even if you nail one of those arteries, you have no guarantee that you will stop the guy at all. I have seen many guys come to hospital with damaged neck vessels and most of them have been in good enough condition to go for an angiogram before going to theatre for repair. By the way, damaging a vertebral artery high up in the neck is almost certainly going to involve damaging the spine, but whether the spinal cord is involved depends on deflection and the angle of incidence of the bullet relative to the person's neck.
One thing that should be made a 'mental sticky' in everyobody's mind is that it takes time to bleed to death. Even if you sever the aorta don't think he will drop just like that: he has time to draw and shoot if he is willing and otherwise able.