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I have shot Nutria, Ground Hogs, and Fox, fartherest shot was 175yrds, with a Volquartsen 22mag loaded with CCI 40gr solids which is still a very accurate set up. But basically anything over 125yrds out to 200 you would be better off with 223 or 22-250. The best I've ever done was a GH at 380yrds with a Sako 22-250 loaded with Hornady 55gr V-max.
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