It all comes down to what you are comfortable with, I have both the GP 100 4" and an SP 101 2" da only. I only carry the SP 101 and find it too heavy for any pocket and carry it in a fobus OWB holster. am waiting on the LGS to get a LCR 22 mag, as I want something a little lighter and more concealable, but thats me. You have to be comfortable with the size, weight, accuracy and energy of whatever you decide to carry. a hit with a 22 mag far out weighs a miss with a 44 mag. and in the case of when you need it most control is key. best of luck to you on whichever you decide. they are both fabulous guns especially with a wolf shooters pack installed.