If you are shooting plinkers, you can get more rounds out of a one pound can using a quicker burning powder. Its been my experience that each weapon will react differently to the powder used. Some like it hot and quick, others like it slow but fast. Most of my autos like HS-6 and AA#5. The 357s like H-110. The 38s seem to like Unique but it is kinda messy and dirty. While I have a good supply of Unique, I don't really load that much of it. If you are happy with the loads using the HS-6, I'd leave it alone.
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