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.243 should be alright if she can shoot it accurately.
I would say a .223 if your state allows and kills are no more than 100 yards away.
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Krav Maga/Judo
Qualified Rifleman/Marksmanship Instructor/Lic. Medic
"There is therefore now no condemnation to those who are in Christ Jesus, who do not walk according to the flesh, but according to the Spirit" Romans 8:1
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