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Stick with powders equal or slower than IMR4350. My best loads have been with IMR4831. As far as 145 grain Speer, if you push them to 3000fps, they will make a real mess. Speer recommends Grand Slams for the 7mmRM. I can verify the mess with 3 deer that each lost a shoulder or ham blown to the ground from 60-165 yards with that bullet at 3130. I went to 154-160 and got normal results.
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