At the range, it makes no difference and I wouldn't be surprised that you would shoot the 8 3/8" better. My 8 3/8" M57 is my best shooting 41 mag. It works well for hunting, but you need some sort of chest/bandoleer type rig to carry it comfortably in the field due to the barrel length. The 6" is clearly easier to carry in the field. So, it's your choice as always.
You loose a little velocity with the 6" barrel too relative to the 8 3/8"; guessing 300 fps or about 150 fps per inch. Not a big deal in terms of killing power.
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