While they seem to have been reasonably popular, it has always seemed to me that a screw barrel gun simply is too time-consuming to reload. Powder and ball can be rammed as fast as a barrel can be unscrewed, and a cartridge will make loading even faster and without the need to carry a powder flask and balls. IMHO, the supposed extra power of the screw barrel does not counteract that greater difficulty, at least in a small pocket pistol.
Jim
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