In the first iteration of this thread someone mentioned this:
"the reliability of a centerfire primer is a lot better than a rimfire round also"
I've not found that to be true.
I've had more factory primer failures with centerfire ammunition than I have with rimfire ammunition over the years, and I've shot metric buttload of both.
The worst was I had a box of Remington revolver ammunition in which 7 cartridges refused to fire.
The only completely dead .22s I've ever had were either really cheap foreign made or old ammo whose storage was questionable.
I have absolutely no problems carrying a .22 pocket pistol.
"The gift which I am sending you is called a dog, and is in fact the most precious and valuable possession of mankind" -Theodorus Gaza
Baby Jesus cries when the fat redneck doesn't have military-grade firepower.