One of the first rifles that Hiram Maxim successfully suppressed was a Model of 1903 Springfield in .30-06 (IIRC).
The amount of gas produced by a full bore .30-06 cartridge is significant, yet the device was so successful that it couldn't be heard 10 yards from the gun.
What could be heard, though, was the sonic crack of the bullet as it passed the telegraph poles on the side of the road Maxim fired down.
Maxim's early designs are proof positive that the amount of gas the cartridge develops is immaterial as long as the silencer is designed to accommodate it.
Interestingly enough, the other thing that Maxim designed?
The first successful mufflers for internal combustion engines.
"The gift which I am sending you is called a dog, and is in fact the most precious and valuable possession of mankind" -Theodorus Gaza
Baby Jesus cries when the fat redneck doesn't have military-grade firepower.