Report and temporary deafness is one thing. But I think flash is more of a concern. I can't find a cite but I believe I have read over 3/4 of home defense firearm use is at night. Temporary deafness is a reduction awareness. Temporary blindness from a flash indoors in the dark is a full loss of awareness for more than a few seconds.
As far as wall penetration this depends on a lot of variables. If you are in a wood frame with many residents it is different than a brick frame with one or two residents