I keep a 12 gauge pump shotgun loaded with #1 buckshots at home.
I also keep a glock 23 in my emergency supply box. We have earthquake in Southern California. In case the big one comes, I can still dig out the boxes (20mm cannon ammo cases) from under the rubbles. The supply will keep our family going for a week on a stretch, and the glock will be the tool for security if needed.
With the glock, I also have drop-in barrels for 9mm Luger and .357 sig, and some other spare parts. Extra ammunitions are stored at separate locations.
I have other pistols. I usually shoot them single-handed bullseye style. But for the glock, it is in two-hand Weaver's stand.