I found that my 22lr suppressor did not change point of impact or change velocity.
I found that my 45-70 suppressor added a very slight amount of speed. Hot loaded ammo gains about 20 fps, sub sonic ammo gained little to nothing.
no where near what even 2 extra inches of barrel would add.
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 23 of my guns are 45/70 govt 357 mag, 22 or 12 ga... I believe in keeping it simple