Most of the time when you see a Blackhawk that is "worn" to the point of something not working right (finish wear doesn't count), it is the result of abuse or mis use rather than over use.
you can screw up, even break a Ruger with enough abuse. And playing cowboy games with a revolver not tuned for it could be enough abuse.
You can even blow them up, if you try hard enough.
But used in the normal way, with normal ammo, and properly cared for, they are nearly immortal.
All else being equal (and it almost never is) bigger bullets tend to work better.