Use that grip pictured, and you'll end up activating your safety and deactivating your gun on the 1911. As long as thumb isn't under the safety unless thumb is down.Thumb ON or UP behind the safety works well on 1911, and other guns as well.
Not an issue with a proper sort of pistol.
"Risk comes from not knowing what you're doing." — Warren Buffett
"You can't go as deep [in] training as in a race or a fight. If you don't compete it's easy to convince yourself you're going hard. You're not." — Mark Twight