I do it all the time with my SP101 in a modified Don Hume's IWB holster. It also allows you to use a thin holster like a Uncle Mike's IWB holster since retension is maintained with the belt. And your pants protect you from the hard parts of the gun. Another advantage I have found is that I sweat less with another ( pants) barrier between me and the holster.
If your in a war, instead of throwing a hand grenade at the enemy, throw one of those small pumpkins. Maybe it'll make everyone think how stupid war is, and while they are thinking, you can throw a real hand grenade at them. www.sendoutcards.com