I shot a Colt King Cobra a few times, it was OK, did not set my world on fire.
I handled a Colt Python once, it didn't give me the giggles either.
I own three K frames and one J frame, they suit me the best.
I shot a Ruger GP-100 a few times, they are heavy!
I shot a Ruger Super Blackhawk a few times, and it was a hoot!
I think, in my opinion, that Colts are nice looking and well finished pieces, but the Colts don't do it for me. Rugers are heavy and overbuilt. (good thing)
My personal choice is S&W all day long for the DA revolver, and when I feel like working with a single action it will be a Ruger.