My CCW is either a gen 3 Glock 19 or a Kahr K9 with 1 or 2 extra mags.
My primary night watch gun is a S&W 6906. I don't/won't keep a gun on the nightstand in the open where someone can get at it. The 6906 is under my pillow with the safety on. Depending on the circumstances, I keep a Glock 34 with a light/laser combo tucked away close to a Mossberg 590.
"By His stripes we are healed..."