Remington is expanding its ammo production facilities. An entirely new company will go into production in North Carolina. I wouldn't pick an uncommon cartridge just because there has been all this madness over the usual cartridges.
Were I starting from scratch, I'd likely get some sort of general purpose rifle (anywhere from an SKS on through a Ruger Scout) and set up to reload for it. Build up a stock of components. I'd add a .22 rimfire or maybe something like the .17 Mach II or the .17 HMR.
It all depends on where you live, what your general usage might be on a day-to-day basis, and your own view of future scenarios.
Not I, not anybody else, can define another person's reality.
You're from BATFE? Come right in! I use all your fine products!