I currently only own two pistols. The one I shot at the range today will be the one on my nightstand tonight.
Mine are both 45 Colts, a 4" Redhawk and a 3.75" birdshead Vaquero.
Getting into warmer weather the Redhawk is spending a lot of time in the safe right now. Getting ready for hunting season long about August first or so I'll start practicing with the Redhawk again.
If I afford a third pistol I'll probably dedicate a Colt p1840 or p1841 to nightstand duty with occasional daytime carry.