If you're having issues getting consistency at 100yds with a 2x, you probably have not matched your target to your scope. You don't need to see a 1" target to shoot 1" groups. You need a target you can consistently bracket your sights or optic against. You can shoot MOA with buckhorns with the right target.
I'm afraid that I don't understand what you stated. Are you saying that your sight picture in the handgun scope should be 1" at 100 yds to be able to shoot well at that distance? If that is the case, I disagree, but we all do things our own way. Even at 6x you will still have a pretty wide field of view. Maybe you can explain. The vertical and horizontal grid lines are there to allow you to "bracket".