I think for the game load I'll stick with the 150 grain load that I've settled on.
If your rifle will shoot them accurately that is what I would do also. I have a Remington 700P in .308. That rifle will not shoot 150/155 grain bullets worth a hoot. I have tried all sorts of load variations and my gun just does not like them. Switch to 168 gr, Federal trophy loads or hand loads with 165/175 bullets and the gun just comes alive. My M1A on the other hand shoots the 145/146/147 milsurp just fine as well as the Federal 168 gr. loads. It is funny that rifles are sometimes so picky that way.