Hey, I live there!
As for the Highway 287 commute, I always take I-80 to I-25 via Cheyenne anyway. 287 is theoretically quicker but in reality having taken about a billion trips to FoCo it's only about 5-10 minutes quicker at most, and slower when it's nasty and slick. Also an extraordinarily dangerous little stretch of road, I have personally known 3 people who died or were crippled on it the 6 years I have been here.
I've been taking 200+ mile drives at night in WY since I was 16. It's not bad if you're an attentive driver but you definitely have to look out for wildlife.
I'll be leaving Laramie in about a year. I love this state but the weather is truly horrible in this part of it.
Beretta PX4 .40 S&W | Beretta 92FS 9x19 Para | Rock Island Armory GI 1911 .45 ACP | Colt Python 4" .357 Magnum | Colt 1968 Det. Spec. .38 Spc. | Ruger LCP .380 ACP | Daniel Defense M4V1 5.56x45 | Alpine M1 Carbine .30 | Steyr M1895 8x56 | Ruger 10/22 .22LR |1943 Izhevsk Mosin-Nagant M91/30 7.62x54R | Remington 870 12GA