I would keep them all, I have around 5k-6K of bullets alone in each caliber, twice that of primers, and around 28lbs of powder, and it doesn't bother me at all. It doesn't cost you anything to let them sit until you need them.
I always keep a year or more of primers and powder, I can always cast my own bullets and have about 300lbs of lead sitting in the shed.
Because I keep a decent stock of supplies I coasted through the last two shortages, and so far I am coasting through this one.
And noylj is completely right, it is getting very lonely at the range. Only us seasoned reloaders that know to keep supplies are still shooting.
The range is out of ammo also, it's eerie quiet in there.