If you go the auto route, no gun will be as comfortable for her as one of the S&W MP's. With the ability to change to small backstrap, it's a guaranteed fit. I own the 45, 4", 8rd model. AWESOME! Puts the Glocks, Springfields, Sigs, and HK's to shame!
Going to have to disagree wholeheartedly with this entire statement. None of us are in any position to say which gun will be the most comfortable for her, and although the M&P is a great gun I don't think it puts any of the guns you listed to shame. All the manufacturers you listed make quality firearms, what's best for one person may not be the best for the other.