It's possible that your reloaded bullets do not have the proper bullet crimp. As you shoot the pistol, the recoil forces the remaining live rounds to work themselves forward from a loose crimp and jam the cylinder. What kind of caliber is the pistol? I've seen it happen on 454 Casull reloads...that some shooter bought at a gunshow.
That rifle hanging on the wall of the working class flat or labourer's cottage is the symbol of democracy. It is our job to see that it stays there."
--- George Orwell