Recoil isn't an issue with .22lr's MOST OF THE TIME. Not being an MD or having the slightest clue what issues you have I can't make any sort of call. But to effectively fire a .22lr you pretty much have to bring it firmly into your shoulder for accurate fire. I'm sure someone may have success not doing that but it's not right.
If you're wanting something more "rifle-like" than a standard handgun look at the Ruger Chargers. Basically a short barreled 10/22 semi without a shoulder stock. Intended to be used with a scope and rests. Mucho aftermarket support if you want to mod it some (not that it's required).