I carry Buffalo Bore 158gr SWCHP, both +P and non-+P, which are all lead, and Speer Gold Dot 125gr +P JHPs, which are copper jacketed lead, in my 38s.
I would not carry a round-nosed bullet in a revolver, lead or jacketed, unless I had no other option. I have no doubt that they are effective in many cases. But I have other choices that I consider better. I am fervently hoping I never find out whether I made a good choice.