The round profile does help with speed loaders, but that's the only advantage that comes to mind. Comes in handy when competing at the range.
If it were legal I'd pop a turkey with one so as to not damage as much meat, but around here it's only leagal to blow their heads off with a 12ga.
I do think lead bullets are great for SD, but as mentioned before a SWC will make a better hole.
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