It amazes me how much lack of knowledge there is about terminal ballistics.
If you hit them in the CNS, you are effective. If you don't, they will have minimum several minutes to do what they want to you and your family. Very likely, a surgeon will remove that super ultra hollow point and they will live a long and healthy life.
Period. End of discussion. Everything else is an incremental improvement in bleed out time or the chances of nicking something important as you miss. If you don't miss, a .380 FMJ will do just fine.