accuracy is fine. each weapon will be slightly different based upon tolerances and ammunition used.
the only issues will be this, the 22 mag uses a larger bullet diameter the the 22lr,22l,22 short. as a result the barrel is sized for 22 mag projectiles. that means the standard 22 lrs have a big of extra bumping up to do. so accuracy will suffer slightly.
just like what happens when a black hawk convertible is used with the 9mm cylinder. a little freebore.