I have owned a PX4 .40 fullsize type F for coming on 5 years now, and coming on 5,000 rounds. It has never skipped a beat, and never given any indication of being anything but excellent quality. It has also fed a wide variety of loads happily, including five shapes of popular carry JHP (HST, Gold Dot, Ranger-T, PDX1, and Remington Golden Saber have all run smooth as silk, if I recall correctly).
It's a fantastic pistol. It was a crazy bargain at the $399 it was going for before the panic, and is still reasonable at the $520-550 it goes for now. I have had some time with the FNP (not FNX or FNS, the current series) and while it was a quality gun, my subjective feel was that the Beretta was nicer. The Beretta magazines are way nicer, but that's true about almost every brand versus the Brescia-made Beretta and Mec-Gar magazines. Italians know how to make a nice mag.
Beretta PX4 .40 S&W - Beretta 92FS 9x19 Para - Rock Island Armory GI 1911 .45 ACP - Colt 1968 Detective Special .38 Spc. - Ruger LCP .380 ACP - Daniel Defense M4V1 Carbine 5.56x45 - Alpine Industries M1 Carbine .30 - Steyr-Mannlicher M1895 8x56 - Ruger 10/22 .22LR - Remington 870 Express Tactical 12GA - 1943 Izhevsk Mosin-Nagant M91/30 7.62x54R