Not in my opinion. As a collector's piece, yes. For a practical shooter, no.
I believe the Smith & Wesson L-Frame Model 586 Distinguished Combat Magnum is the very best .357 Magnum DA revolver to come down the pike.
I'll catch a lot of flak for this statement, but neither the famed Python nor the pre-Model 27 Smith & Wesson .357 Magnum can surpass the L-Framed gun. I have had considerable experience with these as well as Model 28 Highway Patrolmans and Model 19 Combat Magnums, and Dan Wessons.
Now for a single action............