Definitely! If you shop around, you might be able to get a nice levergun in 357 Mag (look for old Marlins or a decent Henry) and any number of good 22s for that easily.
If you want to buy new guns, then a new HiPoint Carbine in 45ACP:
and a CZ455 Lux:
... would be just the ticket! The CZs are very popular and very accurate, with a lively online community to boot. However, don't limit yourself to only what I and others suggest. Get ye to a gun shop and go fondle some rifles!