I've tagged a couple of dozen bucks with the Sierra 85-grain HPBT. Mostly neck shots, of course, but a couple of cross-body heart/lung shots.
That's definitely a blow-up bullet, so I would not take an angling shot on a deer. It does horrible things to feral cats and innocent coyotes, of course.
I get very good groups with a 1:10 twist. Three behind a dime; five-shot groups are 3/4 MOA at most.
You're from BATFE? Come right in! I use all your fine products!