I favor the 35 because of the wide selection of bullets available for reloading. Many 180's and 200's intended for the 35 Rem(including the new FTX) can be loaded to tolerable levels and still be first class deer round out to 200 yards. Sierra's 225gr boattail has legit 300+yard numbers. Nosler and Barnes have the upper end covered.
My Rem 7600 35 Whelen is top end of my arsenal. Full power 250's are as much fun as I can tolerate and I can't think of any critter in the lower 48 I need more gun for.