My Glock 26 goes from the drawer of my bedside table to my holster and back to the drawer. I have a GunVault that usually stays in my car, but can come inside when we have overnight guests. It is loaded and chambered always.
My Beretta 92FS lives in the other bedside table, on my wife's side. It stays loaded and chambered, but decocked. It goes under lock and key if we have company.
Other firearms are kept unloaded and locked up.