Shooting whitetail deer at 225 yards max distance, BC is most assuredly 100% irrelevant. Figure me the difference in the point of impact at 250 yards between two big game bullets with a 150 yard zero in a 10mph cross-wind. BC is irrelevant.
I've never said that a .243 is a "kill everything" caliber but it most certainly is a kill everything up to at least elk size caliber. Shot placement matters, the energy you put in the tree on the other side of the animal doesn't matter. The .041 or .065 difference in the size of the hole is irrelevant.
Still happily answering to the call-sign Peetza.
The problem, as you so eloquently put it, is choice.
He is no fool who gives what he can not keep to gain what he can not lose.
-Jim Eliott, paraphrasing Philip Henry.