Usual warning: While you can probably chamber and fire a modern 22 lr cartridge, it's not a safe thing to do. 6 mm Flobert was weaker than the 22 short. If you want to fire it, have a competent gunsmith determine the correct chambering and condition.
I used to love being able to hit hard at 1000 yards. As I get older I find hitting a mini ram at 200 yards with the 22 oddly more satisfying.