What the heck is "specialized target ammo"?
Generally standard velocity made to exacting specifications and costing dearly. Unless its for steel target shooting it is not a good idea for defending the homestead.
Any 22 will hurt but if you must use a 22 LR for self defense purposes at least get high velocity 40 grain solids, not hyper velocity or hollow points. You need all the help you can get and that means you need to penetrate. A plated 40 grain bullet will break through a bone and get inside to do some damage where a hollow point will deform there and either stop or deflect and go elsewhere at a much reduced velocity. If you have to make small holes make them deep holes, not shallow holes.