Mine's a tie between my cz-75 and my S&W Model 19.
The CZ is my baby. One of the first guns I ever bought, and it was the feel in my hand that pulled me in. I haven't looked back. I put it on my list of guns that I would only trade if I absolutely had to to put food on the table/insulin for the future missus.
The model 19 is a newish piece, and I just love the feel in my hand. Original factory grips (bought off eBay), and it just reminds me how a wheelgun is supposed to feel. Too bad the missus has informaly adopted it.
My favorite is the S&W M19.
My CZ75b feels so similar to the M19 it's spooky.
I have to wonder if they didn't design the 75b so it's critical dimensions would mimic the S&W K frame.
oops- I forgot that one...there I have to agree.
As much as I love the feel of my S&W M19, the 1851 Colt Navy is far and away the best handling gun ever made.