IMHO i think Colt might start making the Snake guns again if all the magazine cap gets past, because if there is mag cap in place, the 6-8 rounds of .357, 44, or 44 Spl. sound more appealing than 10rnd. or less of 9MM, 40 or 45.
I wouldn't bet on it. Ten is still more than six, and if many autoloader buyers really wanted more power, 10mm pistols would sell better. Furthermore, most of the recent growth in the handgun market has been small, lightweight, cheap, and easily concealable carry guns, a description that the Snake Series guns most definitely do not meet.
IMHO Colt would be better off reintroducing the Dick Special.