As far as bullet weight goes, I have killed more deer with a 95 gr. bullet in a 6mm rem. rifle than I have anything else. Ive never had one go more than a few steps if I put the shot where it was supposed to be. Bullet construction is much more important than bullet weight. Energy and velocity also play as important a role as weight. A 110 gr. bullet from a .30 carbine rifle will work great for deer IMO, but a .30 carbine revolver would be more "iffy" than a .357
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