Sure, the Snake series, especially the Python, is highly sought after now, but that's because they don't make them anymore.
Back in the late 80s and early 90s semiauto pistols became popular and demand for revolvers dropped like a stone. (Prices were rock bottom on the used market then too. I bought a mint ANIB Python for $500 in 1992, S&W 14s for $200, etc. Wish I had bought even more.)
Between S&W, Ruger and Colt there was way more production capacity than demand and something had to give. Turned out it was Colt.