I haven't shot the .45, but the .40 and 9mm are excellent.
Is the .45 frame larger than the .40/9mm frame? Because that frame actually feels a bit small in my hands, not large.
Beretta PX4 .40 S&W - Beretta 92FS 9x19 Para - Rock Island Armory GI 1911 .45 ACP - Colt 1968 Detective Special .38 Spc. - Ruger LCP .380 ACP - Daniel Defense M4V1 Carbine 5.56x45 - Ruger 10/22 .22LR - Remington 870 Express Tactical 12GA - 1943 Izhevsk Mosin-Nagant M91/30 7.62x54R