I have a Marlin 44 mag lever gun converted to 50 A.E. ... yes, it can be done, & turns a sweet lil carbine to a BEAST...
if you're thinking a lever gun, finding someone who who could set up one for 357 Remington Maximum would be really cool ( hm... might have to do that
) otherwise with an off the shelf gun, a 44 mag lever would be more "practical" that a 45 Colt because most will feed the 44 specials as well... if you wanted a semi, one in 10mm would be my 1st choice for hunting, 9mm for normal cheapest ammo, but a 40 S&W might have the best factory ammo availability through thick & thin...