I all ready only have 3 Calibers so I guess that works for me.
1. 22LR for small game
2. 357 magnum Carbine for Small game up to Deer (yes I use it frequently on Idaho mule deer)
3. 45-70. For tings bigger than deer.
Where I live its very dense forest. A long shot is 75 yards.
Shot placement is everything! I would rather take a round of 50BMG to the foot than a 22short to the base of the skull.
all 26 of my guns are 45/70 govt, 357 mag, 22 or 12 ga... I believe in keeping it simple. Wish my wife did as well...