I've never shot for groups without a rest but I used to practice regularly on 2" spinners and a 22/45 at 50'. 8 outta 10 was about the norm. But I will say that the last couple years have caught up both in the eyes and steadiness, don't have a clue what I'd do today.
From a rest it's a different matter. I usually shoot on my butt, gun between my knees ala. Keith and depending on the gun 4MOA is pretty normal using open sights.